The potential protein-mediated hepatic uptake: discussion on the molecular interactions between albumin and the hepatocyte cell surface and their implications for the in vitro-to-in vivo extrapolations of hepatic clearance of drugs
Author:
Affiliation:
1. Department of Environmental and Occupational Health, School of Public Health, Université de Montréal, Montreal, Quebec, Canada
2. Consultant Patrick Poulin Inc., Québec city, Canada
Funder
Natural Science and Engineering Research Council of Canada
Publisher
Informa UK Limited
Subject
Pharmacology,Toxicology,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/17425255.2019.1640679
Reference98 articles.
1. Albumin-mediated transport of rose bengal by perfused rat liver. Kinetics of the reaction at the cell surface.
2. Effect of Albumin Binding on Extraction of Sulfobromophthalein by Perfused Elasmobranch Liver: Evidence for Dissociation-Limited Uptake
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