The potential protein-mediated hepatic uptake: discussion on the molecular interactions between albumin and the hepatocyte cell surface and their implications for the in vitro-to-in vivo extrapolations of hepatic clearance of drugs-Reference-Cited by-同舟云学术

The potential protein-mediated hepatic uptake: discussion on the molecular interactions between albumin and the hepatocyte cell surface and their implications for the in vitro-to-in vivo extrapolations of hepatic clearance of drugs

Published:2019-07-18 Issue:8 Volume:15 Page:633-658
ISSN:1742-5255
Container-title:Expert Opinion on Drug Metabolism & Toxicology
language:en
Short-container-title:Expert Opinion on Drug Metabolism & Toxicology

Author:

Bteich Michel¹,Poulin Patrick¹²,Haddad Sami¹^ORCID

Affiliation:

1. Department of Environmental and Occupational Health, School of Public Health, Université de Montréal, Montreal, Quebec, Canada

2. Consultant Patrick Poulin Inc., Québec city, Canada

Funder

Natural Science and Engineering Research Council of Canada

Publisher

Informa UK Limited

Subject

Pharmacology,Toxicology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/17425255.2019.1640679

Reference98 articles.

1. Albumin-mediated transport of rose bengal by perfused rat liver. Kinetics of the reaction at the cell surface.

2. Effect of Albumin Binding on Extraction of Sulfobromophthalein by Perfused Elasmobranch Liver: Evidence for Dissociation-Limited Uptake

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