Mechanistic kinetic modeling generates system-independent P-glycoprotein mediated transport elementary rate constants for inhibition and, in combination with 3D SIM microscopy, elucidates the importance of microvilli morphology on P-glycoprotein mediated efflux activity-Reference-Cited by-同舟云学术

Mechanistic kinetic modeling generates system-independent P-glycoprotein mediated transport elementary rate constants for inhibition and, in combination with 3D SIM microscopy, elucidates the importance of microvilli morphology on P-glycoprotein mediated efflux activity

Published:2018-06-03 Issue:6 Volume:14 Page:571-584
ISSN:1742-5255
Container-title:Expert Opinion on Drug Metabolism & Toxicology
language:en
Short-container-title:Expert Opinion on Drug Metabolism & Toxicology

Author:

Ellens Harma¹,Meng Zhou¹,Le Marchand Sylvain J.¹,Bentz Joe¹

Affiliation:

1. Department of Biology, Drexel University, Philadelphia, PA, USA

Funder

Drexel University

Publisher

Informa UK Limited

Subject

Pharmacology,Toxicology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/17425255.2018.1480720

Reference43 articles.

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