Beyond animal models: implementing the 3Rs principles and improving pharmacological studies with new model systems-Reference-Cited by-同舟云学术

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Beyond animal models: implementing the 3Rs principles and improving pharmacological studies with new model systems

Published:2021-06-30 Issue:8 Volume:17 Page:867-868
ISSN:1742-5255
Container-title:Expert Opinion on Drug Metabolism & Toxicology
language:en
Short-container-title:Expert Opinion on Drug Metabolism & Toxicology

Author:

Giovannetti Elisa¹²,Peters Godefridus¹³

Affiliation:

1. Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam UMC, VU University, Amsterdam, The Netherlands

2. Cancer Pharmacology Lab, Fondazione Pisana per La Scienza, Pisa, Italy

3. Department of Biochemistry, Medical University of Gdansk, Gdansk, Poland

Publisher

Informa UK Limited

Subject

Pharmacology,Toxicology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/17425255.2021.1948731

Reference9 articles.

1. Refining in vitro and in silico neurotoxicity approaches by accounting for interspecies and interindividual differences in toxicodynamics

2. Human induced pluripotent stem cell (iPSC)-derived cardiomyocytes as an in vitro model in toxicology: strengths and weaknesses for hazard identification and risk characterization

3. Organotypic-liver slide culture systems to explore the role of extracellular vesicles in pancreatic cancer metastatic behavior and guide new therapeutic approaches

4. Toward regulatory acceptance and improving the prediction confidence of in silico approaches: a case study of genotoxicity

5. High-throughput PBTK models for in vitro to in vivo extrapolation

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4. SF3B1 modulators affect key genes in metastasis and drug influx: a new approach to fight pancreatic cancer chemoresistance;Cancer Drug Resistance;2021

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