BRAF inhibitors and their immunological effects in malignant melanoma

Author:

Adams Rebecca12,Coumbe Jack E M12,Coumbe Ben G T12,Thomas Jennifer2,Willsmore Zena1,Dimitrievska Marija1,Yasuzawa-Parker Monica1,Hoyle Maximilian1,Ingar Suhaylah1,Geh Jenny L C13,MacKenzie Ross Alastair D3ORCID,Healy Ciaran3,Papa Sophie45,Lacy Katie E1,Karagiannis Sophia N16ORCID

Affiliation:

1. St. John’s Institute of Dermatology, School of Basic & Medical Biosciences, King’s College London, London UK

2. Royal Marsden Hospital, London, UK

3. Department of Plastic Surgery at Guy’s, King's, and St. Thomas' Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK

4. Department of Medical Oncology, Guy’s and St. Thomas’ NHS Foundation Trust, London, UK

5. ImmunoEngineering, School of Cancer and Pharmaceutical Sciences, Faculty of Life Sciences and Medicine, King’s College London, London, UK

6. Breast Cancer Now Research Unit, School of Cancer & Pharmaceutical Sciences, King’s College London, Guy’s Cancer Centre, London UK

Funder

Guy’s and St Thomas’ Foundation Trust Charity, Melanoma Special Fund

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

Reference106 articles.

1. CRUK. Melanoma skin cancer statistics, cancer research UK February 2021. [cited 2022 Jan]. Available from: https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/melanoma-skin-cancerhttps://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/melanoma-skin-cancer. https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/melanoma-skin-cancerhttps://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/melanoma-skin-cancer.

2. Melanoma

3. Distinguishing Clinicopathologic Features of Patients with V600E and V600K BRAF-Mutant Metastatic Melanoma

4. The role of BRAF V600 mutation in melanoma

5. Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation

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