Mitochondrial dysfunction-associated microbiota establishes a transmissible refractory response to anti-TNF therapy during ulcerative colitis-Reference-Cited by-同舟云学术

Mitochondrial dysfunction-associated microbiota establishes a transmissible refractory response to anti-TNF therapy during ulcerative colitis

Published:2023-10-16 Issue:2 Volume:15 Page:
ISSN:1949-0976
Container-title:Gut Microbes
language:en
Short-container-title:Gut Microbes

Author:

Peña-Cearra Ainize¹²^ORCID,Castelo Janire¹^ORCID,Lavín Jose Luis¹³,Gonzalez-Lopez Monika¹^ORCID,Pascual-Itoiz Miguel Angel¹,Fuertes Miguel⁴^ORCID,Gutiérrez de Juan Virginia¹,Bárcena Laura¹,Martín-Ruiz Itziar¹^ORCID,Pellón Aize¹^ORCID,Seoane Iratxe¹,Barriales Diego¹,Palacios Ainhoa¹^ORCID,Fullaondo Asier⁵^ORCID,Rodríguez-Lago Iago⁶^ORCID,Martinez-Chantar María L.¹⁷^ORCID,Aransay Ana Mª¹⁷^ORCID,Rodriguez Hector¹,Anguita Juan¹⁸^ORCID,Abecia Leticia¹²^ORCID

Affiliation:

1. CIC bioGUNE, Basque Research and Technology Alliance (BRTA), Derio, Spain

2. Department of Immunology, Microbiology and Parasitology, Faculty of Medicine and Nursing, University of the Basque Country (UPV/EHU), Bilbao, Spain

3. Applied Mathematics Department, NEIKER-Basque Institute for Agricultural Research and Development, Basque Research and Technology Alliance (BRTA), Derio, Spain

4. Animal Health Department, NEIKER-Basque Institute for Agricultural Research and Development, Basque Research and Technology Alliance (BRTA), Derio, Spain

5. Department of Genetics, Physical Anthropology and Animal Physiology, University of the Basque Country (UPV/EHU), Bilbao, Spain

6. Department of Gastroenterology, Hospital de Galdakao, Galdakao, Spain

7. CIBERehd, ISCIII, Madrid, Spain

8. Ikerbasque, Basque Foundation for Science, Bilbao, Spain

Funder

Spanish Ministry of Economy and Competitiveness co-financed with FEDER funds

GETECCU-MSD (Grupo Español de Trabajo en Enfermedad de Crohn y Colitis ulcerosa to LA), Basque Government project for health

Research Committee from OSI Barrualde-Galdakao

University of the Basque Country (UPV/EHU) and is currently a postdoctoral fellow funded by the Basque Government

Basque Department of Industry, Tourism and Trade (Etortek and Elkartek Programs) and the Innovation Technology Department of Bizkaia County

MINECO for the Severo Ochoa Excellence Accreditation

Publisher

Informa UK Limited

Subject

Infectious Diseases,Microbiology (medical),Gastroenterology,Microbiology

Link

https://www.tandfonline.com/doi/pdf/10.1080/19490976.2023.2266626

Reference40 articles.

1. Primary Failure to an Anti-TNF Agent in Inflammatory Bowel Disease: Switch (to a Second Anti-TNF Agent) or Swap (for Another Mechanism of Action)?

2. Gerriets V, Goyal A, Khaddour K. Tumor necrosis factor inhibitors. Florida: StatPearls. Treasure Island (FL); 2022.

3. Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response

4. Altered intestinal microbiota–host mitochondria crosstalk in new onset Crohn’s disease

5. Mechanisms of Pediatric Inflammatory Bowel Disease