Influence of genetic polymorphisms in vascular endothelial-related genes on the clinical outcome of axitinib in patients with metastatic renal cell carcinoma
Author:
Affiliation:
1. Department of Urology, Akita University Graduate School of Medicine, Akita, Japan
2. Department of Pharmacy, Hirosaki University Hospital, Hirosaki, Japan
3. Department of Pharmacy, Akita University Hospital, Akita, Japan
Funder
Grants-in-Aid for Scientific Research, Japan
Publisher
Informa UK Limited
Link
https://www.tandfonline.com/doi/pdf/10.1080/15384047.2024.2312602
Reference32 articles.
1. Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial
2. Key predictive factors for efficacy of axitinib in first-line metastatic renal cell carcinoma: subgroup analysis in Japanese patients from a randomized, double-blind phase II study
3. Pharmacogenetics-based area-under-curve model can predict efficacy and adverse events from axitinib in individual patients with advanced renal cell carcinoma
4. Contribution of UGT1A1 genetic polymorphisms related to axitinib pharmacokinetics to safety and efficacy in patients with renal cell carcinoma
5. Constitutional genetic variants as predictors of antiangiogenic therapy outcome in renal cell carcinoma
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