STAT3 inhibitor in combination with irradiation significantly inhibits cell viability, cell migration, invasion and tumorsphere growth of human medulloblastoma cells

Author:

Pan Li1,Zhang Ruijie1,Ma Ling1,Pierson Christopher R.2,Finlay Jonathan L.3,Li Chenglong4,Lin Jiayuh1

Affiliation:

1. Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD, USA

2. Department of Pathology and Laboratory Medicine, Nationwide Children’s Hospital, Department of Pathology and Department of Biomedical Education & Anatomy, College of Medicine, The Ohio State University, Columbus, OH USA

3. Division of Hematology, Oncology and BMT, the Research Institute at Nationwide Children’s Hospital, Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, OH USA

4. Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL USA

Funder

NIH/NINDS

National Institute of Neurological Disorders and Stroke

Publisher

Informa UK Limited

Subject

Cancer Research,Pharmacology,Oncology,Molecular Medicine

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