Autophagy-dependent glutaminolysis drives superior IL21 production in HIV-1-specific CD4 T cells

Author:

Loucif Hamza1ORCID,Dagenais-Lussier Xavier1,Avizonis Daina2,Choinière Luc2,Beji Cherifa1,Cassin Léna3,Routy Jean-Pierre4,Fritz Jörg H.5,Olagnier David3,van Grevenynghe Julien1

Affiliation:

1. Institut National de la Recherche Scientifique (INRS)-Centre Armand-Frappier Santé Biotechnologie, Laval, Quebec, Canada

2. Metabolomics Innovation Resource, Rosalind and Morris Goodman Cancer Center, McGill University, Montreal, QC, Canada

3. Department of Biomedicine, Research Center for Innate Immunology, Aarhus University, Aarhus, Denmark

4. Chronic Viral Illness Service and Division of Hematology, McGill University Health Centre, Montreal, Quebec, Canada

5. Department of Microbiology and Immunology, McGill University, Montreal, Quebec, Canada

Funder

Fonds de Recherche du Québec - Santé

Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada

Publisher

Informa UK Limited

Subject

Cell Biology,Molecular Biology

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