Regorafenib induces lethal autophagy arrest by stabilizing PSAT1 in glioblastoma

Author:

Jiang Jingwen1,Zhang Lu1ORCID,Chen Haining2,Lei Yunlong3,Zhang Tao4,Wang Yuelong5,Jin Ping1,Lan Jiang1,Zhou Li1,Huang Zhao1,Li Bowen1,Liu Yuan1,Gao Wei1,Xie Ke6,Zhou Liangxue5,Nice Edouard C.7,Peng Yong1,Cao Yihai8,Wei Yuquan1,Wang Kui1,Huang Canhua1

Affiliation:

1. State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, and West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, P.R. China

2. Department of Gastrointestinal Surgery, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Collaborative Innovation Center for Biotherapy, Chengdu, P.R. China

3. Department of Biochemistry and Molecular Biology, Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing, P.R. China

4. The School of Biomedical Sciences, Chengdu Medical College, Chengdu, P.R. China

5. Department of Neurosurgery, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Collaborative Innovation Center for Biotherapy, Chengdu, P.R. China

6. Department of Oncology, Sichuan Provincial People‘s Hospital, Chengdu, P.R. China

7. Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia

8. Department of Microbiology, Tumour and Cell Biology, Karolinska Institutet, Stockholm, Sweden

Publisher

Informa UK Limited

Subject

Cell Biology,Molecular Biology

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