Hypoxia-induced autophagy drives colorectal cancer initiation and progression by activating the PRKC/PKC-EZR (ezrin) pathway

Author:

Qureshi-Baig Komal1,Kuhn Diana1,Viry Elodie12,Pozdeev Vitaly I.1,Schmitz Martine1,Rodriguez Fabien1,Ullmann Pit1,Koncina Eric1,Nurmik Martin1,Frasquilho Sonia3,Nazarov Petr V.4,Zuegel Nikolaus5,Boulmont Marc5,Karapetyan Yervand3,Antunes Laurent36,Val Daniel6,Mittelbronn Michel6789,Janji Bassam2,Haan Serge1,Letellier Elisabeth1ORCID

Affiliation:

1. Molecular Disease Mechanisms Group, Life Sciences Research Unit, University of Luxembourg, Esch-sur-Alzette, Luxembourg

2. Laboratory of Experimental Cancer Research, Luxembourg Institute of Health, Strassen, Luxembourg

3. Integrated Biobank of Luxembourg, Dudelange, Luxembourg

4. Proteome and Genome Research Unit, Luxembourg Institute of Health, Strassen, Luxembourg

5. Department of Surgery, Centre Hospitalier Emile Mayrisch, Esch-sur-Alzette, Luxembourg

6. Department of Anatomic and Molecular Pathology, Laboratoire National de Santé (LNS), Dudelange, Luxembourg

7. Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-sur-Alzette, Luxembourg

8. NORLUX Neuro-Oncology Laboratory, Luxembourg Institute of Health (LIH), Strassen, Luxembourg

9. Luxembourg Centre of Neuropathology (LCNP), Dudelange, Luxembourg

Funder

Fonds De La Recherche Scientifique - FNRS

Fonds De La Recherche Scientifique - FNRSr

Fonds National de la Recherche Luxembourg

Fondation Cancer

Publisher

Informa UK Limited

Subject

Cell Biology,Molecular Biology

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