CKLF induces microglial activation via triggering defective mitophagy and mitochondrial dysfunction

Author:

Wang Hongyun1,Ye Junrui1,Peng Ye2,Ma Wenyu1,Chen Haodong1,Sun Hongshuo3,Feng Zhongping3,He Wenbin4,Li Gang5,Chu Shifeng1,Zhang Zhao1,Chen Naihong1

Affiliation:

1. State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica & Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

2. School of Pharmacy, Minzu University of China, Beijing, China

3. Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, ON, Canada

4. National International Joint Research Center for Molecular Chinese Medicine, Shanxi University of Chinese Medicine, Shanxi, Taiyuan, China

5. Graduate school, Inner Mongolian Medical University, Hohhot, Inner Mongolia, China

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Key R&D Program of Shanxi Province

CAMS Innovation Fund for Medical Sciences

High-End Foreign Experts introduction program

Publisher

Informa UK Limited

Subject

Cell Biology,Molecular Biology

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