Pharmacokinetics, metabolism, excretion and safety of iruplinalkib (WX-0593), a novel ALK inhibitor, in healthy subjects: a phase I human radiolabeled mass balance study-Reference-Cited by-同舟云学术

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Pharmacokinetics, metabolism, excretion and safety of iruplinalkib (WX-0593), a novel ALK inhibitor, in healthy subjects: a phase I human radiolabeled mass balance study

Published:2024-01-15 Issue: Volume: Page:1-10
ISSN:1354-3784
Container-title:Expert Opinion on Investigational Drugs
language:en
Short-container-title:Expert Opinion on Investigational Drugs

Author:

Bian Yicong¹²^ORCID,Ma Sheng¹²,Yao Qingqing¹,Hu Tao¹,Ge Mingjing³,Li Hongting³,Zheng Shansong³,Gu Zheming⁴,Feng Hao⁴,Yu Zhenwen⁴,Huang Chenrong¹,Zhang Hua¹,Zhao Limei²,Miao Liyan¹

Affiliation:

1. Department of Pharmacy, First Affiliated Hospital of Soochow University, Suzhou, China

2. Department of Pharmacy, Shengjing Hospital of China Medical University, Shenyang, China

3. Qilu Pharmaceutical Co. Ltd., Jinan, China

4. Value Pharmaceutical Services Co., Ltd., Nanjing, China

Funder

National Key New Drug Creation Special Programs

Hospital Pharmacy Committee of Chinese Pharmaceutical Association

National Natural Science Foundation of China

Publisher

Informa UK Limited

Subject

Pharmacology (medical),Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/13543784.2024.2305134

Reference21 articles.

1. Current treatment and future challenges in ROS1- and ALK-rearranged advanced non-small cell lung cancer

2. Systemic Therapy for Locally Advanced and Metastatic Non–Small Cell Lung Cancer

3. First-Line Crizotinib versus Chemotherapy in ALK-Positive Lung Cancer

4. Crizotinib in ROS1-Rearranged Non–Small-Cell Lung Cancer

5. Understanding and targeting resistance mechanisms in NSCLC

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