Short-term inhalation of sargramostim with concomitant high-dose steroids does not hasten recovery in moderate COVID-19 pneumonia: a double-blind, randomised, placebo-controlled trial-Reference-Cited by-同舟云学术

Short-term inhalation of sargramostim with concomitant high-dose steroids does not hasten recovery in moderate COVID-19 pneumonia: a double-blind, randomised, placebo-controlled trial

Published:2023-09-20 Issue:12 Volume:55 Page:857-873
ISSN:2374-4235
Container-title:Infectious Diseases
language:en
Short-container-title:Infectious Diseases

Author:

Shimasaki Shigeki¹,Baba Tomohisa²,Ogura Takashi²,Akasaka Keiichi³,Matsushima Hidekazu³,Izumi Shinyu⁴,Takasaki Jin⁴,Tsushima Kenji⁵,Kinouchi Toru⁵,Kichikawa Yoshiko⁶,Awashima Maiko⁶,Izumo Takehiro⁷,Awano Nobuyasu⁷,Nishimura Naoki⁸,Tazawa Ryushi⁹,Mikami Ayako¹⁰,Kitamura Nobutaka¹¹,Ishii Haruyuki¹²,Kurihara Yasuyuki¹³,Taniguchi Masaki¹,Aikawa Satoko¹,Okada Mami¹,Morita Yusuke¹,Ishikawa Yuko¹,Ohinata Akira¹,Nakata Koh¹⁴

Affiliation:

1. Nobelpharma Co., Ltd, Chuo-ku, Japan

2. Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan

3. Department of Respiratory Medicine, Saitama Red Cross Hospital, Saitama, Japan

4. Department of Respiratory Medicine, National Center for Global Health and Medicine, Shinjuku-ku, Japan

5. Department of Pulmonary Medicine, International University of Health and Welfare (IUHW), Chiba, Japan

6. Department of Respiratory Medicine, Federation of National Public Service Personnel Mutual Aid Associations, Mishuku Hospital, Meguro-ku, Japan

7. Department of Respiratory Medicine, Japanese Red Cross Medical Center, Shibuya-ku, Japan

8. Department of Pulmonary Medicine, Thoracic Center, St. Luke’s International Hospital, Chuo-ku, Japan

9. Health Administration Center, Student Support and Health Administration Organization, Tokyo Medical and Dental University, Bunkyo-ku, Japan

10. National Center for Global Health and Medicine, Center for Clinical Sciences, Shinjuku-ku, Japan

11. Clinical and Translational Research Center, Niigata University Medical and Dental Hospital, Niigata, Japan

12. Department of Respiratory Medicine, Kyorin University School of Medicine, Mitaka, Japan

13. Department of Radiology, St. Luke’s International Hospital, Chuo-ku, Japan

14. Center for Medical Innovation, Division of Pioneering Advanced Therapeutics, Niigata University Medical Dental Hospital, Niigata, Japan

Publisher

Informa UK Limited

Subject

Infectious Diseases,Microbiology (medical),General Immunology and Microbiology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/23744235.2023.2254380

Reference29 articles.

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2. Ministry of Health Labour and Welfare. Situation report. [Internet]. [cited 2022 November 7]. Available from: https://www.mhlw.go.jp/stf/covid-19/kokunainohasseijoukyou_00006.html.

3. Clinical management of patients with COVID-19: a guide for front-line healthcare workers. Version 2.1. JAPAN COVID-19 Case Management Guide Review Committee. [Internet]. [cited 2022 July 9]. Available from: https://www.niph.go.jp/h-crisis/wp-content/uploads/2020/07/20200706103735_content_000646510.pdf. [In Japanese].

4. Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia

5. Cytokine Storm: The Primary Determinant for the Pathophysiological Evolution of COVID-19 Deterioration