Experimental Study of Fluidized Bed Co-Granulation of Two Active Pharmaceutical Ingredients: An Industrial Scale-Up Perspective

Author:

Bilgili Ecevit,Rosen Lawrence A.,Ko Jeff S.,Chen Adam,Smith Edward J.,Fliszar Kyle,Wong Gordon

Publisher

Informa UK Limited

Subject

General Chemical Engineering

Reference28 articles.

1. Akkermans , J. H. M. M. F. Edwards , A. T. J. Groot , C. P. M. Montanus , R. W. J. Van Pomeren , and K. R. Yuregir . 1998 . Production of Detergent Granules, Patent WO9858046.

2. The effect of droplet size and powder particle size on the mechanisms of nucleation and growth in fluid bed melt agglomeration

3. Fluidised-Bed Granulation: A Chronology

4. Bilgili , E. J. Ko , A. Chen , E. Smith , P. Rajniak , K. Fliszar , G Wong , L. Rosen , D. Grubb , and D. Bika . 2007 . Controlling the key response variables through scaling rules during the scale-up of a fluidized bed granulation process. Annual Meeting of the AIChE, Paper No: 553d, Salt Lake City, Utah, November.

5. Bilgili , E. L. Schenck , B. Sell , K. Gallagher , H. Young , T. S. Chen , and D. Bika . 2007 . Development of a fluidized bed granulation process: A comparative analysis with two different formulations. Annual Meeting of the AIChE, Paper No: 159d, Salt Lake City, Utah, November.

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