Screening of active components in Astragalus mongholicus Bunge and Panax notoginseng formula for anti-fibrosis in CKD: nobiletin inhibits Lgals1/PI3K/AKT signaling to improve renal fibrosis

Author:

Yang Fang123,Li Tong2,Zhang Xiao-qian12,Gong Yi12,Su Hongwei4,Fan Junming5ORCID,Wang Li2,Hu Qiong-dan12,Tan Rui-zhi2

Affiliation:

1. Department of Nephrology, the Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, China

2. Research Center of Integrated Traditional Chinese and Western Medicine, the Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, China

3. Department of Nephrology, Sichuan Integrative Medicine Hospital, Chengdu, China

4. Department of Urology, the Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, China

5. Department of Nephrology, the First Affiliated Hospital of Chengdu Medical College, Chengdu, China

Funder

the Sichuan Science and Technology Program

the Luzhou-Southwest Medical University Science and Technology Strategic Cooperation Project

the Innovation Team of Affiliated Traditional Medicine Hospital of Southwest Medical University

Publisher

Informa UK Limited

Reference49 articles.

1. Prevalence of Chronic Kidney Disease in China

2. Myofibroblast in Kidney Fibrosis: Origin, Activation, and Regulation

3. Traditional and complementary medicine for promoting healthy ageing in WHO Western Pacific Region: Policy implications from utilization patterns and current evidence

4. Clinical efficacy analysis of Renal Impotence Formula in the treatment of non-dialysis patients with chronic kidney disease stage 3-5;Mao N;World Chin Med,2018

5. Clinical efficacy observation of Astragalus mongholicus Bunge and Panax notoginseng formula in primary nephrotic syndrome;Xie XS;Chin J Integr Chin Western Med Nephrol,2012

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