Prescription patterns of antiseizure drugs in tuberous sclerosis complex (TSC)-associated epilepsy: a multicenter cohort study from Germany and review of the literature

Author:

Strzelczyk Adam123ORCID,Grau Janina12,Bast Thomas4,Bertsche Astrid5,Bettendorf Ulrich6,Hahn Andreas7,Hartmann Hans8,Hertzberg Christoph9,Hornemann Frauke10,Immisch Ilka3,Jacobs Julia1112,Klotz Kerstin A.1113,Kluger Gerhard1415,Knake Susanne3,Knuf Markus1617,Kurlemann Gerhard18,Marquard Klaus19,Mayer Thomas20,Meyer Sascha21,Muhle Hiltrud22,Müller-Schlüter Karen23,von Podewils Felix24,Rosenow Felix12ORCID,Ruf Susanne25,Sauter Matthias26,Schäfer Hannah2728,Schlump Jan-Ulrich29,Schubert-Bast Susanne1230ORCID,Syrbe Steffen31,Thiels Charlotte32,Trollmann Regina33,Wiemer-Kruel Adelheid4,Wilken Bernd34,Zukunft Bianca35,Zöllner Johann Philipp12

Affiliation:

1. Goethe-University Frankfurt, Frankfurt am Main, Germany

2. LOEWE Center for Personalized Translational Epilepsy Research (CePTER), Goethe-University Frankfurt, Frankfurt am Main, Germany

3. Epilepsy Center Hessen and Department of Neurology, Philipps-University Marburg, Marburg, Germany

4. Epilepsy Center Kork, Clinic for Children and Adolescents, Kehl-Kork, Germany

5. Department of Neuropediatrics, University Hospital for Children and Adolescents, Rostock, Germany

6. Neuropediatric Practice, Hirschaid, Germany

7. Department of Neuropediatrics, Justus-Liebig-University Gießen, Gießen, Germany

8. Clinic for Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Hannover, Germany

9. Department of Neuropediatrics, Vivantes Klinikum Neukölln, Berlin, Germany

10. Department of Neuropediatrics, Leipzig University Hospital for Children and Adolescents, Leipzig, Germany

11. Department of Neuropediatrics and Muscle Disorders, Center for Pediatrics, Medical Center, University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg i.Br., Germany

12. Department of Pediatrics and Clinical Neurosciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

13. Berta-Ottenstein-Programme, Faculty of Medicine, University of Freiburg, Freiburg i.Br., Germany

14. Clinic for Neuropediatrics and Neurorehabilitation, Epilepsy Center for Children and Adolescents, Schön Klinikum Vogtareuth, Germany

15. Research Institute, Rehabilitation, Transition and Palliation, PMU Salzburg, Salzburg, Austria

16. Department of Pediatrics, Helios Dr. Horst Schmidt Kliniken Wiesbaden, Wiesbaden, Germany

17. Department of Pediatrics, University Medicine Mainz, Mainz, Germany

18. Child Neurology, St. Bonifatius Hospital, Lingen, Germany

19. Department of Pediatric Neurology, Psychosomatics and Pain Management, Klinikum of Stuttgart, Stuttgart, Germany

20. Epilepsy Center Kleinwachau, Dresden-Radeberg, Germany

21. Department of Neuropediatrics, University Children´s Hospital of Saarland, Homburg, Germany

22. Department of Neuropediatrics, Christian-Albrechts-University Kiel & University Hospital Schleswig-Holstein, Campus Kiel, Germany

23. Epilepsy Center for Children, University Hospital Neuruppin, Brandenburg Medical School, Neuruppin, Germany

24. Departmental of Neurology, Epilepsy Center, University Medicine Greifswald, Greifswald, Germany

25. Department of Neuropediatrics, University Hospital Tübingen, Tübingen, Germany

26. Klinikum Kempten, Klinikverbund Allgäu, Kempten/Allgäu, Germany

27. Division of Nephrology, Medizinische Klinik Und Poliklinik IV, Klinikum der LMU München - Innenstadt, München, Germany

28. Department of Nephrology, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany

29. Department of Neuropediatrics, University of Witten/Herdecke, Herdecke, Germany

30. Department of Neuropediatrics, Goethe-University Frankfurt, Frankfurt am Main, Germany

31. Division of Pediatric Epileptology, Center for Pediatrics and Adolescent Medicine, University Hospital Heidelberg, Heidelberg, Germany

32. Department of Neuropediatrics and Social Pediatrics, St. Josef-Hospital, University Hospital of Pediatrics and Adolescent Medicine, Ruhr-University Bochum, Bochum, Germany

33. Department of Neuropediatrics, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, Germany

34. Department of Neuropediatrics, Klinikum Kassel, Kassel, Germany

35. Department of Nephrology and Internal Intensive Care, Charité - University Medicine Berlin, Berlin, Germany

Funder

State of Hessen with a LOEWE-Grant to the CePTER Consortium

Publisher

Informa UK Limited

Subject

Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics,General Medicine

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