Identification of 3-(piperazinylmethyl)benzofuran derivatives as novel type II CDK2 inhibitors: design, synthesis, biological evaluation, and <i>in silico</i> insights-Reference-Cited by-同舟云学术

Identification of 3-(piperazinylmethyl)benzofuran derivatives as novel type II CDK2 inhibitors: design, synthesis, biological evaluation, and in silico insights

Published:2022-04-26 Issue:1 Volume:37 Page:1227-1240
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Eldehna Wagdy M.¹²,Maklad Raed M.²³,Almahli Hadia⁴,Al-Warhi Tarfah⁵,Elkaeed Eslam B.⁶,Abourehab Mohammed A. S.⁷,Abdel-Aziz Hatem A.⁸,El Kerdawy Ahmed M.⁹¹⁰

Affiliation:

1. School of Biotechnology, Badr University in Cairo, Badr City, Egypt

2. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt

3. Institute of Drug Discovery and Development, Kafrelsheikh University, Kafrelsheikh, Egypt

4. Department of Chemistry, University of Cambridge, Cambridge, UK

5. Department of Chemistry, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia

6. Department of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Riyadh, Saudi Arabia

7. Department of Pharmaceutics, Faculty of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia

8. Department of Applied Organic Chemistry, National Research Center, Dokki, Egypt

9. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt

10. Department of Pharmaceutical Chemistry, School of Pharmacy, NewGiza University (NGU), Cairo, Egypt

Funder

The Deanship of Scientific Research at Princess Nourah Bint Abdulrahman University

Umm Al-Qura University

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/14756366.2022.2062337

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