Discovery of benzochromene derivatives first example with dual cytotoxic activity against the resistant cancer cell MCF-7/ADR and inhibitory effect of the P -glycoprotein expression levels

Author:

Al-Harbi Laila M.1,Al-Harbi Eman A.2,Okasha Rawda M.2ORCID,El-Eisawy R. A.34,El-Nassag Mohammed A. A.3,Mohamed Hany M.35,Fouda Ahmed M.6,Elhenawy Ahmed A.37ORCID,Mora Ahmed3,El-Agrody Ahmed M.3ORCID,El-Mawgoud Heba K. A.8

Affiliation:

1. Chemistry Department, Faculty of Science, King Abdul-Aziz University, Jeddah, Saudi Arabia

2. Chemistry Department, Faculty of Science, Taibah University, Medina, Saudi Arabia

3. Chemistry Department, Faculty of Science, Al-Azhar University, Cairo, Egypt

4. Chemistry Department, Faculty of Science and Art, Al-Baha University, Al-Baha, Saudi Arabia

5. Chemistry Department, Faculty of Science, Jazan University, Jazan, Saudi Arabia

6. Chemistry Department, Faculty of Science, King Khalid University, Abha, Saudi Arabia

7. Chemistry Department, Faculty of Science and Art, AlBaha University, Al Bahah, Saudi Arabia

8. Chemistry Department, Faculty of Women for Arts, Science, and Education, Ain Shams University, Cairo, Egypt

Funder

the Deanship of Science Research at King Khalid University, Saudi Arabia

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

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4. Ultrasonic-assisted ruthenium-catalyzed oxidation of aromatic and heteroaromatic compounds

5. Recent applications of multicomponent reactions in medicinal chemistry

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