Design, synthesis, and biological evaluation of novel ciprofloxacin derivatives as potential anticancer agents targeting topoisomerase II enzyme

Author:

Swedan Hadeer K.1,Kassab Asmaa E.2,Gedawy Ehab M.23,Elmeligie Salwa E.2

Affiliation:

1. Central Administration of Research and Health Development, Ministry of Health, and Population (MoHP), Cairo, Egypt

2. Faculty of Pharmacy, Department of Pharmaceutical Organic Chemistry, Cairo University, Cairo, Egypt

3. Faculty of Pharmacy and Pharmaceutical Industries, Department of Pharmaceutical Chemistry, Badr University in Cairo (BUC), Badr City, Egypt

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Reference78 articles.

1. World Health Organization. Cancer [Internet]. Geneva (Switzerland): WHO; 2021 [cited 2022 Feb 3]. Available from: https://www.who.int/news-room/fact-sheets/detail/cancer.

2. On the origin of cancer foci

3. Diagnosis and Treatment of Metastatic Colorectal Cancer

4. The Different Mechanisms of Cancer Drug Resistance: A Brief Review

5. Topoisomerase Assays

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