Molecular pharmacology of multitarget cyclin-dependent kinase inhibitors in human colorectal carcinoma cells

Author:

Manohar Sonal M.1,Joshi Kalpana S.2

Affiliation:

1. Department of Biological Sciences, Sunandan Divatia of School of Science, NMIMS (Deemed-to-be) University, Mumbai, India

2. Discovery Engine, Cipla R and D, Cipla Ltd, Mumbai, India

Funder

Piramal Life Sciences Ltd

Publisher

Informa UK Limited

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Medicine

Reference56 articles.

1. Colorectal cancer: global drug forecast and market analysis to 2028. April 2020. https://store.globaldata.com/report/gdhc182pidr–colorectal-cancer-global-drug-forecast-and-market-analysis-to-2028/ (accessed on Dec 25, 2020).

2. Eukaryotes arose after genetic recombination

3. Selective inhibition of proliferation in colorectal carcinoma cell lines expressing mutant APC or activated B-Raf

4. Colon carcinoma cells harboringPIK3CAmutations display resistance to growth factor deprivation induced apoptosis

5. PIK3CA mutations confer resistance to first-line chemotherapy in colorectal cancer

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