Curcumin analog, GO-Y078, induces HO-1 transactivation-mediated apoptotic cell death of oral cancer cells by triggering MAPK pathways and AP-1 DNA-binding activity

Author:

Chien Ming-Hsien1234,Shih Pei-Chun5,Ding Yi-Fang67,Chen Li-Hsin1,Hsieh Feng-Koo8,Tsai Meng-Ying910,Li Pei-Yi11,Lin Chiao-Wen1112,Yang Shun-Fa910

Affiliation:

1. Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan

2. TMU Research Center of Cancer Translational Medicine, Taipei Medical University, Taipei, Taiwan

3. Pulmonary Research Center, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan

4. Traditional Herbal Medicine Research Center, Taipei Medical University Hospital Taipei, Taiwan

5. Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan

6. Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan

7. Department of Otolaryngology, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan

8. Department of Orthopaedic Surgery, School of Medicine, Washington University, St. Louis, MO, USA

9. Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan

10. Department of Medical Research, Chung Shan Medical University Hospital, Taichung, Taiwan

11. Graduate Institute of Oral Sciences, Chung Shan Medical University, Taichung, Taiwan

12. Department of Dentistry, Chung Shan Medical University Hospital, Taichung, Taiwan

Funder

Chung Shan Medical University Hospital

Publisher

Informa UK Limited

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Medicine

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