Defibrotide: potential for treating endothelial dysfunction related to viral and post-infectious syndromes

Author:

Richardson Edward12,García-Bernal David3,Calabretta Eleonora45,Jara Rubén6,Palomo Marta78,Baron Rebecca M.9,Yanik Gregory1011,Fareed Jawed12,Vlodavsky Israel13,Iacobelli Massimo14,Díaz-Ricart Maribel81516,Richardson Paul G.1917,Carlo-Stella Carmelo1459,Moraleda Jose M.3ORCID

Affiliation:

1. Frank H. Netter M.D. School of Medicine at Quinnipiac University, North Haven, Connecticut, USA

2. Department of Surgery, Yale University School of Medicine, New Haven, Connecticut, USA

3. Department of Medicine, Stem Cell Transplant and Cell Therapy Unit, IMIB-Arrixaca, Virgen De La Arrixaca University Hospital, University of Murcia, Murcia, Spain

4. Department of Biomedical Sciences, Humanitas University, Rozzano-Milano, Italy

5. Department of Oncology and Hematology, IRCCS - Humanitas Research Hospital, Rozzano-Milano, Italy

6. Intensive Care Unit, Virgen De La Arrixaca University Hospital, University of Murcia, Murcia, Spain

7. Josep Carreras Leukaemia Research Institute, Hospital Clinic, University of Barcelona, Barcelona, Spain

8. Barcelona Endothelium Team, Barcelona, Spain

9. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

10. Department of Pediatrics, Blood and Marrow Transplantation Program, University of Michigan, Ann Arbor, MI, USA

11. Department of Internal Medicine, Blood and Marrow Transplantation Program, University of Michigan, Ann Arbor, Michigan, USA

12. Department of Molecular Pharmacology and Therapeutics, Hemostasis and Thrombosis Research Laboratories, Loyola University Medical Center, Chicago, Illinois, USA

13. Technion Integrated Cancer Center, Rappaport Faculty of Medicine, Technion, Haifa, Israel

14. Techitra S.r.l., Milan, Italy

15. Hematopathology, Pathology Department, CDB, Hospital Clinic, Barcelona, Spain

16. IDIBAPS, Barcelona, Spain

17. Division of Hematologic Malignancy, Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA

Funder

the Instituto de Salud Carlos III

Publisher

Informa UK Limited

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Medicine

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