Synthesis of 4-Amino-8-(2, 2-Difluoro-2-Deoxy-β-D-Ribo Furanosyl Amino)Pyrimido [5, 4-D]Pyrimidine (dFARPP). Stability and Cellular Cytotoxicity
Author:
Publisher
Informa UK Limited
Subject
Genetics,Biochemistry
Reference19 articles.
1. 1990. Presented in part at 22nd National Medicinal Chemistry Symposium, Austin TX. July 29-August 21990.
2. The synthesis of 4-amino-8-(β--ribofuranosyl)aminopyrimido[5,4-]pyrimidine from a purine nucleoside: a novel rearrangement of the purine ring
3. Synthesis and biological evaluation of certain 2'-deoxy-.beta.-D-ribo-and 2.beta.-D-arabinofuranosyl nucleosides of purine-6-carboxamide and 4,8-diaminopyrimido[5,4-d]pyrimidine
4. Synthesis and antiviral activity of certain 9-.beta.-D-ribofuranosylpurine-6-carboxamides
5. Antitumor and antiviral activity of synthetic .alpha.- and .beta.-ribonucleosides of certain substituted pyrimido[5,4-d]pyrimidines: a new synthetic strategy for exocyclic aminonucleosides
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1. Bicyclic 6 + 6 systems: the chemistry of pyrimido[4,5-d]pyrimidines and pyrimido[5,4-d]pyrimidines;RSC Advances;2019
2. Recent Progress in Pyrimido[5,4-d]pyrimidine Chemistry;Advances in Heterocyclic Chemistry;2015
3. 6-Carbohydrazonamidepurines: Convenient Precursors for 4,8-Disubstituted Pyrimido[5,4-d]pyrimidines;Synlett;2013-12-19
4. ChemInform Abstract: Synthesis of 4-Amino-8-(2,2-difluoro-2-deoxy-β-D-ribofuranosyl amino)pyrimido(5,4-d)pyrimidine (DFARPP). Stability and Cellular Cytotoxicity.;ChemInform;2010-08-18
5. Synthesis and in vitro evaluation of substituted pyrimido[5,4-d]pyrimidines as a novel class of Antimycobacterium tuberculosis agents;European Journal of Medicinal Chemistry;2010-07
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