Stress-deprivation induces an up-regulation of versican and connexin-43 mRNA and protein synthesis and increased ADAMTS-1 production in tendon cells in situ-Reference-Cited by-同舟云学术

Stress-deprivation induces an up-regulation of versican and connexin-43 mRNA and protein synthesis and increased ADAMTS-1 production in tendon cells in situ

Published:2021-01-19 Issue:1 Volume:63 Page:43-52
ISSN:0300-8207
Container-title:Connective Tissue Research
language:en
Short-container-title:Connective Tissue Research

Author:

Egerbacher Monika¹,Gardner Keri²,Caballero Oscar²,Hlavaty Juraj¹,Schlosser Sarah³,Arnoczky Steven P.²,Lavagnino Michael²⁴

Affiliation:

1. Histology & Embryology, Department of Pathobiology, University of Veterinary Medicine, Vienna, Austria

2. Laboratory for Comparative Orthopaedic Research, Michigan State University, East Lansing, MI, USA

3. VetCORE Facility for Research, University of Veterinary Medicine, Vienna, Austria

4. Department of Mechanical Engineering, Michigan State University, East Lansing, MI, USA

Publisher

Informa UK Limited

Subject

Cell Biology,Molecular Biology,Orthopedics and Sports Medicine,Biochemistry,Rheumatology

Link

https://www.tandfonline.com/doi/pdf/10.1080/03008207.2021.1873302

Reference48 articles.

1. Tendon Cell Array Isolation Reveals a Previously Unknown Fibrillin-2-Containing Macromolecular Assembly

2. Evidence that interfibrillar load transfer in tendon is supported by small diameter fibrils and not extrafibrillar tissue components

3. Matrix Metalloproteinase Inhibitors Prevent a Decrease in the Mechanical Properties of Stress-Deprived Tendons

4. Re-establishment of cytoskeletal tensional homeostasis in lax tendons occurs through an actin-mediated cellular contraction of the extracellular matrix

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4. Stress deprivation of tendon explants or Tpm3.1 inhibition in tendon cells reduces F-actin to promote a tendinosis-like phenotype;Molecular Biology of the Cell;2022-12-01

5. Allogeneic Serum and Macromolecular Crowding Maintain Native Equine Tenocyte Function in Culture;Cells;2022-05-05