Tumor associated macrophages as key contributors and targets in current and future therapies for melanoma

Author:

Habib Shabana1,Osborn Gabriel1,Willsmore Zena1,Chew Min Waye1,Jakubow Sophie1,Fitzpatrick Amanda123,Wu Yin124,Sinha Khushboo5,Lloyd-Hughes Hawys6,Geh Jenny L. C.56,MacKenzie-Ross Alastair D6ORCID,Whittaker Sean1,Sanz-Moreno Victoria7,Lacy Katie E.1,Karagiannis Sophia N13,Adams Rebecca1

Affiliation:

1. St. John’s Institute of Dermatology, School of Basic & Medical Biosciences, King’s College London, London, UK

2. Oncology Department, Guy’s and St Thomas’ Hospital, London, UK

3. Breast Cancer Now Research Unit, School of Cancer & Pharmaceutical Sciences, King’s College London, Innovation Hub, Guy’s Hospital, London, UK

4. Peter Gorer Department of Immunobiology, School of Immunology & Microbial Sciences, King’s College London, London, UK

5. St John’s Institute of Dermatology, Guy’s, King’s and St. Thomas’ Hospitals NHS Foundation Trust, London, England

6. Department of Plastic Surgery, Guy’s, King’s and St. Thomas’ Hospitals, London, England

7. The Breast Cancer Now Toby Robins Research Centre, Division of Breast Cancer Research, The Institute of Cancer Research, London

Funder

Medical Research Council

Cancer Research UK

King’s College London

British Skin Foundation

Breast Cancer Now

National Institute for Health Research

Department of Health

Wellcome Trust

Publisher

Informa UK Limited

Reference159 articles.

1. Data NC. Cancer incidence and mortality. 2022 [cited 2023]. Available from: https://wwwcancerdata.nhs.uk/incidenceandmortality:NHSCancerData

2. Tumor-associated macrophages in tumor metastasis: biological roles and clinical therapeutic applications

3. Ultraviolet Radiation and Melanomagenesis: From Mechanism to Immunotherapy

4. Unraveling the crosstalk between melanoma and immune cells in the tumor microenvironment

5. JD W How Is Immunotherapy For Melanoma Changing The Outlook For Patients? [cited 2023 Nov 12]. https://www.cancerresearch.org/cancer-types/melanoma2023

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