VEGFC/VEGFR3 Signaling Regulates Mouse Spermatogonial Cell Proliferation via the Activation of AKT/MAPK and Cyclin D1 Pathway and Mediates the Apoptosis by affecting Caspase 3/9 and Bcl-2

Author:

Zhao Liangyu1,Zhu Zijue1,Yao Chencheng1,Huang Yuhua1,Zhi Erlei1,Chen Huixing1,Tian Ruhui1,Li Peng1,Yuan Qingqing2,Xue Yunjing1,Wan Zhong1,Yang Chao1,Gong Yuehua1,He Zuping2,Li Zheng1

Affiliation:

1. Department of Andrology, Center for Men's Health, Institute of Urology, Urologic Medical Center, Shanghai General Hospital, Shanghai Key Lab of Reproductive Medicine, Shanghai Jiao Tong University, School of Medicine, Shanghai, China

2. State Key Laboratory of Oncogenes and Related Genes, Renji- Med X Clinical Stem Cell Research Center, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China

Funder

National Natural Science Foundation of China

The national high-tech research and development program (863) of China

The frontier technology project of Shanghai

Publisher

Informa UK Limited

Subject

Cell Biology,Developmental Biology,Molecular Biology

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