Cergutuzumab amunaleukin (CEA-IL2v), a CEA-targeted IL-2 variant-based immunocytokine for combination cancer immunotherapy: Overcoming limitations of aldesleukin and conventional IL-2-based immunocytokines-Reference-Cited by-同舟云学术

Cergutuzumab amunaleukin (CEA-IL2v), a CEA-targeted IL-2 variant-based immunocytokine for combination cancer immunotherapy: Overcoming limitations of aldesleukin and conventional IL-2-based immunocytokines

Published:2017-01-11 Issue:3 Volume:6 Page:e1277306
ISSN:2162-402X
Container-title:OncoImmunology
language:en
Short-container-title:OncoImmunology

Author:

Klein Christian¹,Waldhauer Inja¹,Nicolini Valeria G.¹,Freimoser-Grundschober Anne¹,Nayak Tapan²,Vugts Danielle J.³,Dunn Claire¹,Bolijn Marije³,Benz Jörg²,Stihle Martine²,Lang Sabine¹,Roemmele Michaele¹,Hofer Thomas¹,van Puijenbroek Erwin¹,Wittig David¹^ORCID,Moser Samuel¹,Ast Oliver¹,Brünker Peter¹,Gorr Ingo H.⁴,Neumann Sebastian²,de Vera Mudry Maria Cristina²^ORCID,Hinton Heather¹,Crameri Flavio²,Saro Jose¹^ORCID,Evers Stefan¹^ORCID,Gerdes Christian¹,Bacac Marina¹,van Dongen Guus³,Moessner Ekkehard¹,Umaña Pablo¹

Affiliation:

1. Roche Pharma Research & Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland

2. Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel, Switzerland

3. Roche Pharma Research & Early Development, Department of Radiology & Nuclear Medicine, VU University Medical Center, Amsterdam, the Netherlands

4. Roche Pharma Research & Early Development, Roche Innovation Center Munich, Penzberg, Germany

Publisher

Informa UK Limited

Subject

Oncology,Immunology,Immunology and Allergy

Link

https://www.tandfonline.com/doi/pdf/10.1080/2162402X.2016.1277306

Reference67 articles.

1. IL-2 Family of Cytokines in T Regulatory Cell Development and Homeostasis

2. The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design

3. The role of interleukin-2 during homeostasis and activation of the immune system

4. Interleukin-2: Biology, Design and Application

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