CD4+ T cell-derived IL-22 enhances liver metastasis by promoting angiogenesis

Author:

Zhang Tao12,Wahib Ramez3,Zazara Dimitra E.45,Lücke Jöran123,Shiri Ahmad Mustafa1,Kempski Jan126,Zhao Lilan3,Agalioti Theodora3,Machicote Andres Pablo12,Giannou Olympia7,Belios Ioannis4,Jia Rongrong12,Zhang Siwen12,Tintelnot Joseph68,Seese Hannes3,Grass Julia Kristin3,Mercanoglu Baris3,Stern Louisa3,Scognamiglio Pasquale3,Fard-Aghaie Mohammad3,Seeger Philipp3,Wakker Jonas3,Kemper Marius3,Brunswig Benjamin3,Duprée Anna3,Lykoudis Panagis M.910,Pikouli Anastasia9,Giorgakis Emmanouil1112,Stringa Pablo13,Lausada Natalia13,Gentilini Maria Virginia14,Gondolesi Gabriel E.13,Bachmann Kai3,Busch Philipp3,Grotelüschen Rainer3,Maroulis Ioannis C.15,Arck Petra C.4,Nakano Ryosuke16,Thomson Angus W.1617,Ghadban Tarik3,Tachezy Michael3,Melling Nathaniel3,Achilles Eike-Gert18,Puelles Victor G.1920,Nickel Felix3,Hackert Thilo3,Mann Oliver3,Izbicki Jakob R.3,Li Jun3,Gagliani Nicola123,Huber Samuel12,Giannou Anastasios D.123

Affiliation:

1. Section of Molecular Immunology and Gastroenterology, I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

2. Hamburg Center for Translational Immunology (HCTI), University Medical Center Hamburg-Eppendorf, Hamburg, Germany

3. Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

4. Division for Experimental Feto-Maternal Medicine, Department of Obstetrics and Fetal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

5. Department of Pediatrics, University Children’s Hospital, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

6. Mildred Scheel Cancer Career Center HaTriCS4, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

7. Computer Engineering & Informatics Dept, University of Patras, Patras, Greece

8. ll. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

9. 3rd Department of Surgery, National & Kapodistrian University of Athens, Athens, Greece

10. Division of Surgery & Interventional Science, University College London (UCL), London, UK

11. Winthrop P Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA

12. Division of Transplantation, Department of Surgery, University of Arkansas for Medical Sciences, Little Rock, AR, USA

13. Department General Surgery, Liver, Pancreas and Intestinal Transplantation, Hospital Universitario, Fundacion Favaloro, Buenos Aires, Argentina

14. Instituto de Medicina Traslacional, Trasplante y Bioingeniería (IMETTyB, CONICET, Universidad Favaloro), Laboratorio de Inmunología asociada al Trasplante, Buenos Aires, Argentina

15. Department of Surgery, University of Patras Medical School, Patras, Greece

16. Department of Surgery, Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

17. Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

18. Department of Visceral Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

19. III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

20. Department of Clinical Medicine, Aarhus University, Aarhus, Denmark

Funder

Deutsche Forschungsgemeinschaft

Publisher

Informa UK Limited

Subject

Oncology,Immunology,Immunology and Allergy

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