Monovalent Omicron COVID-19 vaccine triggers superior neutralizing antibody responses against Omicron subvariants than Delta and Omicron bivalent vaccine

Author:

Li Wanting1,Zhao Tiantian2,Tao Bai3,Zhao Liwei4,Xiao Hang5,Ding Xinyu6,Li Chuang4,Chen Lin7,Cheng Hao5,Lou Yang5,Chen Yuxin48,Wu Chao18

Affiliation:

1. Department of Infectious Diseases, Nanjing Drum Tower Hospital Clinical College of Xuzhou Medical University, Nanjing, Jiangsu, China

2. Department of Infectious Disease, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China

3. Department of Infectious Diseases, Wuhan Jinyintan Hospital, Tongji Medical College of Huazhong University of Science and Technology, Hubei Clinical Research Center for Infectious Diseases, Wuhan, Hubei, China

4. Department of Laboratory Medicine, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China

5. Yurogen Biosystem LLC, Wuhan, Hubei, China

6. Department of Biological Engineering, Nanjing University of Science and Technology, Nanjing, Jiangsu, China

7. Department of Laboratory Medicine, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, Jiangsu, China

8. Institute of Viruses and Infectious Diseases, Nanjing University, Nanjing, Jiangsu, China

Funder

the Training Program of the Major Research Plan of the National Natural Science Foundation of China

the Scientific Research Project of Jiangsu Health Commission

the Major Research Plan of the National Natural Science Foundation of China

Clinical Trials from the Affiliated Drum Tower Hospital, Medical School of Nanjing University

Publisher

Informa UK Limited

Subject

Pharmacology,Immunology,Immunology and Allergy

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