COVID vaccine efficacy against the B.1.351 (“South African”) variant—The urgent need to lay the groundwork for possible future challenge studies

Author:

Eyal Nir12ORCID,Caplan Arthur3ORCID,Plotkin Stanley4

Affiliation:

1. Center for Population-Level Bioethics and Department of Philosophy, Rutgers University, New Brunswick, NJ, USA

2. Department of Health Behavior, Society and Policy, Rutgers School of Public Health, Piscataway, NJ, USA

3. Division of Medical Ethics, Grossman School of Medicine, New York University Langone, New York, NY, USA

4. Emeritus Professor Department of Pediatrics, University of Pennsylvania. Vaxconsult, Doylestown, PA, USA

Funder

U.S. Department of Health and Human Services- National Institutes of Health

National Science Foundation

Open Philanthropy

Publisher

Informa UK Limited

Subject

Pharmacology,Immunology,Immunology and Allergy

Reference15 articles.

1. Antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7

2. SARS-CoV-2 501Y.V2 escapes neutralization by South African COVID-19 donor plasma

3. Moderna. Moderna COVID-19 vaccine retains neutralizing activity against emerging variants first identified in the U.K. and the Republic of South Africa; 2021. [accessed 2021 April 14]. https://investors.modernatx.com/news-releases/news-release-details/moderna-covid-19-vaccine-retains-neutralizing-activity-against.

4. Neutralizing Activity of BNT162b2-Elicited Serum

5. Boseley S. WHO backs use of Oxford/AstraZeneca Covid vaccine for adults of all ages. Guardian. 2021.

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