1. a Laboratory of Pharmacoinformatics and Nanotechnology Department of Biological Science and Technology , China Medical University , Taichung , 40402 , Taiwan
2. b Graduate Institute of Chinese Medical Science, China Medical University , Taichung , 40402 , Taiwan
3. c Terry Fox Cancer Research Lab , China Medical University Hospital , Taichung , 40402 , Taiwan
4. d Department of Medical Genetics Pediatrics and Medical Research , China Medical University Hospital and College of Chinese Medicine China Medical University , Taichung , 40402 , Taiwan
5. e Department of Bioinformatics , Asia University , Taichung , 41354 , Taiwan
6. f Department of Healthcare Administration , Asia University , Taichung , 41354 , Taiwan
7. g Department of Biological Engineering and Center for Cancer Research , Massachusetts Institute of Technology , Cambridge , MA , 02139 , USA