Development of new benzil-hydrazone derivatives as anticholinesterase inhibitors: synthesis, X-ray analysis, DFT study and <i>in vitro</i> / <i>in silico</i> evaluation-Reference-Cited by-同舟云学术

Development of new benzil-hydrazone derivatives as anticholinesterase inhibitors: synthesis, X-ray analysis, DFT study and in vitro / in silico evaluation

Published:2024-01-09 Issue: Volume: Page:1-16
ISSN:0739-1102
Container-title:Journal of Biomolecular Structure and Dynamics
language:en
Short-container-title:Journal of Biomolecular Structure and Dynamics

Author:

Tabbiche Abdelkader¹²³,Bouchama Abdelaziz¹²,Fadli Khadidja¹²,Ahmad Basharat⁴,Kumar Neeraj⁵^ORCID,Chiter Chaabane²,Yahiaoui Messaoud²,Zaidi Farouk¹²,Boudjemaa Kaouther⁶,Dege Necmi⁷,Djedouani Amel⁸⁹,Chafai Nadjib¹⁰^ORCID

Affiliation:

1. Laboratoire de Chimie, Ingénierie Moléculaire et Nanostructures, Université Ferhat Abbas, Sétif, Algeria

2. Département de Chimie, Faculté des Sciences, Université Ferhat Abbas, Sétif, Algérie

3. Biotechnology Research Center, Ali Mendjli Nouvelle Ville UV03, Constantine, Algérie

4. Hazara University Mansehra, Mansehra, Pakistan

5. Department of Pharmaceutical Chemistry, B.N. College of Pharmacy, Udaipur, India

6. University of Mentouri Brothers, Constantine, Algeria

7. Department of Physics, Faculty of Arts and Sciences, Ondokuz Mayis University, Samsun, Turkey

8. Ecole Normale Supérieure de Constantine, Constantine, Algeria

9. Laboratory of Analytical Physicochemistry and Crystallochemistry of Organometallic and Biomolecular Materials, UFMC1, Constantine, Algeria

10. Laboratory of Electrochemistry of Molecular Materials and Complex (LEMMC), Department of Process Engineering, Faculty of Technology, University of Ferhat ABBAS, Sétif, Algeria

Publisher

Informa UK Limited

Link

https://www.tandfonline.com/doi/pdf/10.1080/07391102.2023.2301683

Reference52 articles.

1. Alzheimer's disease prediction based on continuous feature representation using multi-omics data integration

2. Synthesis, single crystal X-ray, spectroscopic and computational (DFT) studies 2,1-benzothiazine based hydrazone derivatives

3. Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase

4. Novel aryl(4-phenylpiperazin-1-yl)methanethione derivatives as new anti-Alzheimer agents: Design, synthesis, in vitro and in silico assays

5. Discovery of novel PARP-1 inhibitors using tandem in silico studies: integrated docking, e-pharmacophore, deep learning based de novo and molecular dynamics simulation approach