Negative allosteric modulators of cannabinoid receptor 2: protein modeling, binding site identification and molecular dynamics simulations in the presence of an orthosteric agonist-Reference-Cited by-同舟云学术

Negative allosteric modulators of cannabinoid receptor 2: protein modeling, binding site identification and molecular dynamics simulations in the presence of an orthosteric agonist

Published:2019-02-05 Issue:1 Volume:38 Page:32-47
ISSN:0739-1102
Container-title:Journal of Biomolecular Structure and Dynamics
language:en
Short-container-title:Journal of Biomolecular Structure and Dynamics

Author:

Pandey Pankaj¹^ORCID,Roy Kuldeep K.¹²^ORCID,Doerksen Robert J.¹³^ORCID

Affiliation:

1. Department of BioMolecular Sciences, Division of Medicinal Chemistry, School of Pharmacy, The University of Mississippi, University, MS, USA;

2. National Institute of Pharmaceutical Education and Research (NIPER), Kolkata, India;

3. Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS, USA

Funder

Division of Chemistry

NIH

XSEDE

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

Link

https://www.tandfonline.com/doi/pdf/10.1080/07391102.2019.1567384

Reference84 articles.

1. Allosteric Modulators: A Side Door

2. The future of type 1 cannabinoid receptor allosteric ligands

3. Examining the critical roles of human CB2 receptor residues Valine 3.32 (113) and Leucine 5.41 (192) in ligand recognition and downstream signaling activities

4. Antibacterial Activity of the Essential Oil from Rosmarinus offi cinalis and its Major Components against Oral Pathogens

5. Potent Anti-Inflammatory and Antiproliferative Effects of Gambogic Acid in a Rat Model of Antigen-Induced Arthritis

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