New nicotinamide derivatives as potential anticancer agents targeting VEGFR-2: design, synthesis, <i>in vitro</i> , and <i>in silico</i> studies-Reference-Cited by-同舟云学术

New nicotinamide derivatives as potential anticancer agents targeting VEGFR-2: design, synthesis, in vitro , and in silico studies

Published:2023-12-15 Issue: Volume: Page:1-18
ISSN:0739-1102
Container-title:Journal of Biomolecular Structure and Dynamics
language:en
Short-container-title:Journal of Biomolecular Structure and Dynamics

Author:

Yousef Reda G.¹,Eissa Ibrahim H.¹^ORCID,Elkady Hazem¹^ORCID,Eldehna Wagdy M.²^ORCID,Mehany Ahmed B. M.³,Nabeeh Ahmed⁴,Ibrahim Ibrahim M.⁵,Elwan Alaa¹,El-Zahabi Mohamed Ayman¹

Affiliation:

1. Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt

2. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt

3. Zoology Department, Faculty of Science (Boys), Al-Azhar University, Cairo, Egypt

4. Zoology Department, Faculty of Science, Mansoura University, Mansoura, Egypt

5. Biophysics Department, Faculty of Science, Cairo University, Cairo, Egypt

Funder

Science, Technology & Innovation Funding Authority

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

Link

https://www.tandfonline.com/doi/pdf/10.1080/07391102.2023.2294170

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2. Gallic acid potentiates the apoptotic effect of paclitaxel and carboplatin via overexpression of Bax and P53 on the MCF‐7 human breast cancer cell line

3. 1-Piperazinylphthalazines as potential VEGFR-2 inhibitors and anticancer agents: Synthesis and in vitro biological evaluation

4. GROMACS: High performance molecular simulations through multi-level parallelism from laptops to supercomputers

5. Targeting VEGFR‐2 by new quinoxaline derivatives: Design, synthesis, antiproliferative assay, apoptosis induction, and in silico studies