In SilicoStructure-Based Design of a Potent and Selective Small Peptide Inhibitor of Protein Tyrosine Phosphatase 1B, A Novel Therapeutic Target for Obesity and Type 2 Diabetes Mellitus: A Computer Modeling Approach
Author:
Publisher
Informa UK Limited
Subject
Molecular Biology,General Medicine,Structural Biology
Link
http://www.tandfonline.com/doi/pdf/10.1080/10256018808623883
Reference23 articles.
1. Protein tyrosine phosphatases: their role in insulin action and potential as drug targets
2. Association of Protein Tyrosine Phosphatase 1B Gene Polymorphisms With Measures of Glucose Homeostasis in Hispanic Americans
3. Association of Protein Tyrosine Phosphatase 1B Gene Polymorphisms With Type 2 Diabetes
4. Increased Insulin Sensitivity and Obesity Resistance in Mice Lacking the Protein Tyrosine Phosphatase-1B Gene
5. Increased Energy Expenditure, Decreased Adiposity, and Tissue-Specific Insulin Sensitivity in Protein-Tyrosine Phosphatase 1B-Deficient Mice
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1. Protein tyrosine phosphatase 1B (PTP1B) function, structure, and inhibition strategies to develop antidiabetic drugs;FEBS Letters;2024-05-09
2. Discovery of a latent calcineurin inhibitory peptide from its autoinhibitory domain by docking, dynamic simulation, and in vitro methods;Journal of Biomolecular Structure and Dynamics;2015-08-06
3. Classification of Binding Site Conformations of Protein Tyrosine Phosphatase 1B;Chemical Biology & Drug Design;2012-04-27
4. Identification of the Structural Features that Mediate Binding Specificity in the Recognition of STAT Proteins by Dual-Specificity Phosphatases;Journal of Biomolecular Structure and Dynamics;2012-02
5. Role of Ligand Binding in Structural Organization ofAddA-riboswitch Aptamer: A Molecular Dynamics Simulation;Journal of Biomolecular Structure and Dynamics;2011-10
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