Phenylalanine 4-monooxygenase: the “sulfoxidation polymorphism”
Author:
Affiliation:
1. Section of Computational and Systems Medicine, Faculty of Medicine, Imperial College London, London, UK;
2. ADMET Solutions Ltd., Basingstoke, UK
Publisher
Informa UK Limited
Subject
Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/00498254.2019.1636419
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1. Thiodiglycolic acid as a possible causative agent of fixed drug eruption provoked only after continuous administration of S-carboxymethyl-l-cysteine: case report and review of reported cases
2. Phenylalanine assembly into toxic fibrils suggests amyloid etiology in phenylketonuria
3. Metabolic profile of XK469 (2(R)-[4-(7-chloro-2-quinoxalinyl)oxyphenoxy]-propionic acid; NSC698215) in patients and in vitro: low potential for active or toxic metabolites or for drug–drug interactions
4. Post-translational activation of human phenylalanine 4-monooxygenase from an endobiotic to a xenobiotic enzyme by reactive oxygen and reactive nitrogen species
5. Cerebrospinal fluid levels of chlorpromazine and its metabolites in schizophrenia
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1. Phenylalanine monooxygenase and the ‘sulfoxidation polymorphism’; the salient points;Drug Metabolism and Personalized Therapy;2022-06-17
2. Classic Pentachlorophenol Hydroxylating Phenylalanine 4-Monooxygenase from Indigenous Bacillus tropicus Strain AOA-CPS1: Cloning, Overexpression, Purification, Characterization and Structural Homology Modelling;Applied Biochemistry and Biotechnology;2021-08-20
3. Whole-genome sequencing, genome mining, metabolic reconstruction and evolution of pentachlorophenol and other xenobiotic degradation pathways in Bacillus tropicus strain AOA-CPS1;Functional & Integrative Genomics;2021-02-06
4. Role of tetrachloro-1,4-benzoquinone reductase in phenylalanine hydroxylation system and pentachlorophenol degradation in Bacillus cereus AOA-CPS1;International Journal of Biological Macromolecules;2020-10
5. Structure, Antioxidant and Anti-inflammatory Activities of the (4R)- and (4S)-epimers of S-Carboxymethyl-L-cysteine Sulfoxide;Pharmaceuticals;2020-09-25
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