Impact of tectoridin on the pharmacokinetics of florfenicol via targeting cytochrome P450 and P-glycoprotein of rats

Author:

Zhang Min12,Wang Bin12,Li Xu-ting12,Yin Qin1,Liang Ge12,Li Si-cong12

Affiliation:

1. Sichuan Key Laboratory of Animal Genetics and Breeding, Sichuan Animal Science Academy, Chengdu, China

2. Veterinary Natural Medicine Research and GCP Experimental Animal Centre, Lezhi, China

Funder

the Program Sichuan Veterinary Medicine and Drug Innovation Group of China Agricultural Research System

the Special Project for Basic Scientific Research and Operating Expenses of The Public Welfare Research Institute of Sichuan Province

Major Science and Technology Projects of the ‘14th Five Year Plan’ in Sichuan Province

Sichuan Provincial Scientific Research Institute Scientific and Technological Achievements Transformation Project

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Reference34 articles.

1. Inhibitory effects of flavonoids on P-glycoprotein in vitro and in vivo: Food/herb-drug interactions and structure–activity relationships

2. A comparative study on the inhibitory actions of chloramphenicol, thiamphenicol and some fluorinated derivatives

3. Committee for Medicinal Products for Human Use (CHMP). 2012. Guideline on bioanalytical method validation. London: European Medicines Agency (EMA).

4. Influences of Re Du Ning Injection, a traditional Chinese medicine injection, on the CYP450 activities in rats using a cocktail method

5. Comparison of levels of several human microsomal cytochrome P-450 enzymes and epoxide hydrolase in normal and disease states using immunochemical analysis of surgical liver samples;Guengerich FP;J Pharmacol Exp Ther,1991

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