Identification of novel scaffolds to inhibit human mitotic kinesin Eg5 targeting the second allosteric binding site using in silico methods
Author:
Affiliation:
1. Department of Biotechnology, School of Chemical and Biotechnology, SASTRA University, Thanjavur, India
Funder
Science and Engineering Research Board
Publisher
Informa UK Limited
Subject
Cell Biology,Molecular Biology,Biochemistry
Link
https://www.tandfonline.com/doi/pdf/10.1080/10799893.2017.1387922
Reference29 articles.
1. A kinesin motor in a force-producing conformation
2. Mitotic functions of kinesin-5
3. Individual dimers of the mitotic kinesin motor Eg5 step processively and support substantial loads in vitro
4. Kinesin-5, a mitotic microtubule-associated motor protein, modulates neuronal migration
5. The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks
Cited by 5 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Comparative Study of Molecular Interaction of Quercetin and B4S With Kinensin-5 Protein In-Silico for the selective anticancer activity of Quercetin;CARDIOMETRY;2023-02-14
2. Comparative Study of Molecular Interactions of Thymol and B4S with Kinesin-5 In-Silico for the Selective Anti-cancer Activity of Thymol;CARDIOMETRY;2023-02-14
3. Role of KSP Inhibitors as Anti-Cancer Therapeutics: An Update;Anti-Cancer Agents in Medicinal Chemistry;2022-08
4. Lead Generation for Human Mitotic Kinesin Eg5 Using Structure-based Virtual Screening and Validation by In-vitro and Cell-based Assays;Current Computer-Aided Drug Design;2021-12
5. Synthesis, cytotoxic assessment, and molecular docking studies of 2,6-diaryl-substituted pyridine and 3,4- dihydropyrimidine-2(1H)-one scaffolds;TURKISH JOURNAL OF CHEMISTRY;2020-02-11
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3