Isometamidium chloride alters redox status, down-regulates p53 and PARP1 genes while modulating at proteomic level in Drosophila melanogaster-Reference-Cited by-同舟云学术

Isometamidium chloride alters redox status, down-regulates p53 and PARP1 genes while modulating at proteomic level in Drosophila melanogaster

Published:2023-03-08 Issue: Volume: Page:1-11
ISSN:0148-0545
Container-title:Drug and Chemical Toxicology
language:en
Short-container-title:Drug and Chemical Toxicology

Author:

Dangabar Shadrack Apollos¹²³,Garba Auwalu²³,Samuel Ndidi Uche²³,Aminu Suleiman²³,Muhammad Aliyu²³⁴

Affiliation:

1. Department of Food Technology and Home Economics, National Agricultural Extension Research and Liaison Services, Ahmadu Bello University, Zaria, Nigeria

2. Department of Biochemistry, Faculty of Life Sciences, Ahmadu Bello University, Zaria, Nigeria

3. Africa Center of Excellence on Neglected Tropical Diseases and Forensic Biotechnology (ACENTDFB), Zaria, Nigeria

4. Center for Biomedical Research, Tuskegee University, Tuskegee, AL, USA

Funder

African Center of Excellence on Neglected Tropical Diseases and Forensic Biotechnology

Publisher

Informa UK Limited

Subject

Chemical Health and Safety,Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health,Pharmacology,Toxicology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/01480545.2023.2186314

Reference77 articles.

1. Ovotoxicants 4-vinylcyclohexene 1,2-monoepoxide and 4-vinylcyclohexene diepoxide disrupt redox status and modify different electrophile sensitive target enzymes and genes in Drosophila melanogaster

2. [13] Catalase in vitro

3. Silver nanoparticles induced heat shock protein 70, oxidative stress and apoptosis in Drosophila melanogaster

4. Acute toxicity of samorin (Isometamidium chloride) in rabbits