Assessment of the Cepheid 3-gene Host Response Fingerstick Blood Test (MTB-HR) on rapid diagnosis of tuberculosis

Author:

Wu Xiaocui12,Tan Guangkun3,Ma Jian4,Yang Juan5,Guo Yinjuan1,Lu Haiwen6,Ke Hui5,Li Mengran7,Tang Yi-Wei4,Sha Wei5,Yu Fangyou18ORCID

Affiliation:

1. Department of Clinical Laboratory, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, People’s Republic of China

2. Shanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China

3. Department of Clinical Laboratory, Shanghai University of Traditional Chinese Medical Attached Shuguang Hospital, Shanghai, People’s Republic of China

4. Medical Affairs, Danaher Diagnostic Platform People’s Republic of China/Cepheid, Shanghai, People’s Republic of China

5. Department of Tuberculosis, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, People’s Republic of China

6. Department of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, People’s Republic of China

7. Department of Biostatistics & Data Management, Beckman Coulter People’s Republic of China, Danaher, Shanghai, People’s Republic of China

8. Department of Laboratory Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People’s Republic of China

Funder

Shanghai clinical research center for infectious disease

Cepheid Investigator-Initiated Study award

Publisher

Informa UK Limited

Subject

Virology,Infectious Diseases,Drug Discovery,General Medicine,Immunology,Microbiology,Parasitology,Epidemiology

Reference18 articles.

1. WHO. Practical manual on tuberculosis laboratory strengthening 2022 update 2023.

2. Organization WH. High-priority target product profiles for new tuberculosis diagnostics: report of a consensus meeting. 2014.

3. A systematic review of biomarkers to detect active tuberculosis

4. Genome-wide expression for diagnosis of pulmonary tuberculosis: a multicohort analysis

5. Assessment of Validity of a Blood-Based 3-Gene Signature Score for Progression and Diagnosis of Tuberculosis, Disease Severity, and Treatment Response

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