HLA-Bw4 in association with KIR3DL1 favors natural killer cell-mediated protection against severe COVID-19

Author:

Wang Ruihua1,Sun Ying1,Kuang Bo-Hua2,Yan Xiao13,Lei Jinju4,Lin Yu-Xin1,Tian Jinxiu1,Li Yating1,Xie Xiaoduo3ORCID,Chen Tao5ORCID,Zhang Hui6ORCID,Zeng Yi-Xin1ORCID,Zhao Jincun5ORCID,Feng Lin1ORCID

Affiliation:

1. Department of Experimental Research, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China

2. Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China

3. Department of Biochemistry, School of Medicine, Sun Yat-sen University, Shenzhen, People’s Republic of China

4. Cancer Center, Renmin Hospital of Wuhan University, Wuhan, People’s Republic of China

5. State Key Laboratory of Respiratory Disease at People’s Hospital of Yangjiang, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People’s Republic of China

6. Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, People’s Republic of China

Funder

National Outstanding Youth Science Fund Project of National Natural Science Foundation of China Nature Science Fund for Excellent Young Scholars

National Natural Science Foundation of China

Medical Foundation

High level project of People's Hospital of Yangjiang

Publisher

Informa UK Limited

Subject

Virology,Infectious Diseases,Drug Discovery,General Medicine,Immunology,Microbiology,Parasitology,Epidemiology

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