Targeted next-generation sequencing of Mycobacterium tuberculosis from patient samples: lessons learned from high drug-resistant burden clinical settings in Bangladesh

Author:

Uddin Mohammad Khaja Mafij1,Cabibbe Andrea Maurizio2,Nasrin Rumana1,Ghodousi Arash2,Nobel Fahim Alam1,Rahman S. M. Mazidur1,Ahmed Shahriar1,Ather Md. Fahim1,Razzaque S. M. Abdur3,Raihan Md. Abu4,Modak Pronab Kumar5,Berland Jean Luc6,Gemert Wayne Van7,Mohsin Sardar Munim Ibna8,Cirillo Daniela Maria2,Banu Sayera1

Affiliation:

1. Infectious Diseases Division, icddr,b, Dhaka, Bangladesh

2. Emerging Bacterial Pathogens Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy

3. National Institute of Disease of the Chest and Hospital, Dhaka, Bangladesh

4. 250 bed TB Hospital, Dhaka, Bangladesh

5. National Tuberculosis Control Programme, Bangladesh

6. Fondation Merieux, Lyon, France

7. Stop TB Partnership, Switzerland

8. Office of Population, Health, and Nutrition, U.S. Agency for International Development (USAID), Bangladesh

Funder

United States Agency for International Development (USAID) through the Stop TB Partnership/ the United Nations Office for Project Services

Publisher

Informa UK Limited

Reference43 articles.

1. Viney K Linh NN Gegia M et al. New definitions of pre-extensively and extensively drug-resistant tuberculosis: update from the World Health Organization. Eur Respiratory Soc; 2021.

2. Report WGT. Global Tuberculosis Report 2023; 2023.

3. World Health Organization. WHO consolidated guidelines on tuberculosis. Module 4: treatment-drug-resistant tuberculosis treatment 2022 update. World Health Organization; 2022.

4. Lifescience H. GenoType MTBDRplus VER 2.0: Molecular genetic assay for identification of the M. tuberculosis complex and its resistance to rifampicin and isoniazid from clinical specimens and cultivated samples. Nehren: Hain Lifescience GmbH; 2012.

5. Evaluation of Genotype MTBDRsl Assay to Detect Drug Resistance Associated with Fluoroquinolones, Aminoglycosides and Ethambutol on Clinical Sediments

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