Mechanisms underlying delayed loss of HBeAg and HBV DNA following HBsAg seroclearance in PEG-IFNα treated patients of chronic hepatitis B-Reference-Cited by-同舟云学术

Mechanisms underlying delayed loss of HBeAg and HBV DNA following HBsAg seroclearance in PEG-IFNα treated patients of chronic hepatitis B

Published:2025-04-03 Issue:1 Volume:14 Page:
ISSN:2222-1751
Container-title:Emerging Microbes & Infections
language:en
Short-container-title:Emerging Microbes & Infections

Author:

Jiang Bei¹²³,Guan Guiwen¹,Zhao Kaitao⁴⁵⁶,Gu Zhiqiang¹,Wang Lin¹⁷,Gu Weilin¹,Li Minghui¹,Xia Yuchen⁴⁵⁶^ORCID,Chen Xiangmei¹⁷,Guo Yifei⁸⁹,Zhang Jiming⁸⁹,Cao Zhenhuan¹⁰¹¹,Yuen Man-fung¹²¹³,Lu Fengmin¹⁷^ORCID

Affiliation:

1. Peking University Health Science Center

2. Tianjin Second People’s Hospital

3. Tianjin Institute of Hepatology

4. Institute of Medical Virology

5. TaiKang Medical School

6. Wuhan University

7. Shenzhen Blood Center, Shen Zhen, Guangdong, People’s Republic of China

8. Shanghai Medical College

9. Fudan University

10. Beijing Youan Hospital

11. Capital Medical University

12. Queen Mary Hospital

13. The University of Hong Kong

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Publisher

Informa UK Limited

Link

https://www.tandfonline.com/doi/pdf/10.1080/22221751.2025.2475847

Reference36 articles.

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3. Hepatitis B Virus Infection — Natural History and Clinical Consequences

4. Countdown to 2030: eliminating hepatitis B disease, China;Liu J;Bull W H O,2019

5. Integrated HBV DNA and cccDNA maintain transcriptional activity in intrahepatic HBsAg-positive patients with functional cure following PEG-IFN-based therapy;Gao N;Aliment Pharmacol Ther,2023