Human hepatocyte-enriched miRNA-192-3p promotes HBV replication through inhibiting Akt/mTOR signalling by targeting ZNF143 in hepatic cell lines

Author:

Li Fahong12ORCID,Deng Yingying3,Zhang Shenyan1,Zhu Beidi1,Wang Jun1,Wang Jinyu1,Wang Xueyu2,Zhao Zhenyu3,Deng Wanyu4ORCID,Mao Richeng1,Shen Zhongliang1,Chen Jieliang5,Broering Ruth6,Lin Yong23ORCID,Lu Mengji2,Zhang Jiming157ORCID

Affiliation:

1. Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, Shanghai Institute of Infectious Diseases and Biosecurity, National Medical Center for Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, People’s Republic of China

2. Institute for Virology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

3. Key Laboratory of Molecular Biology of Infectious Diseases (Chinese Ministry of Education), Chongqing Medical University, Chongqing, People’s Republic of China

4. Department of Biliary Pancreatic Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, People’s Republic of China

5. Key Laboratory of Medical Molecular Virology (MOE/MOH), Shanghai Medical College, Fudan University, Shanghai, People’s Republic of China

6. Department of Gastroenterology and Hepatology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

7. Department of Infectious Diseases, Jing’An Branch of Huashan Hospital, Fudan University, Shanghai, People’s Republic of China

Funder

National Natural Science Foundation of China

Shanghai Shen Kang Hospital Development Center

Shanghai Key Clinical Specialty Construction Program

Shang Rao Science and Technology Department

Medical Faculty of University Duisburg-Essen

Publisher

Informa UK Limited

Subject

Virology,Infectious Diseases,Drug Discovery,General Medicine,Immunology,Microbiology,Parasitology,Epidemiology

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