Recent developments and strategies for the discovery of TACE inhibitors
Author:
Affiliation:
1. Faculty of Pharmacy, Kalabhavan Campus, The Maharaja Sayajirao University of Baroda, Vadodara, India
Publisher
Informa UK Limited
Subject
Drug Discovery
Link
https://www.tandfonline.com/doi/pdf/10.1080/17460441.2020.1744559
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1. Harnessing the natural inhibitory domain to control TNFα Converting Enzyme (TACE) activity in vivo
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3. Role of tumour necrosis factor alpha converting enzyme (TACE/ADAM17) and associated proteins in coronary artery disease and cardiac events
4. Active Metalloproteases of the A Disintegrin And Metalloprotease (ADAM) Family: Biological Function and Structure
5. Astacins, serralysins, snake venom and matrix metalloproteinases exhibit identical zinc-binding environments (HEXXHXXGXXH and Met-turn) and topologies and should be grouped into a common family, the ‘metzincins’
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