Structural requirements for inhibitors of cytochromes P450 2B: Assessment of the enzyme interaction with diamondoids

Author:

Hodek Petr1,Bořek-Dohalská Lucie1,Sopko Bruno1,Šulc Miroslav1,Smrček Stanislav2,Hudeček Jiří1,Janků Josef3,Stiborová Marie1

Affiliation:

1. Department of Biochemistry, Faculty of Science, Charles University, Hlavova 2030, Prague 2, CZ-12840, Czech Republic

2. Department of Organic Chemistry, Faculty of Science, Charles University, Hlavova 2030, Prague 2, CZ-12840, Czech Republic

3. Department of Environmental Chemistry, Prague Institute of Chemical Technology, Technická 5, Prague 6, CZ-16628, Czech Republic

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

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2. Perspective;The Chemistry of Diamondoids;2024-03-22

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4. Toxicology of carbon nanostructures. Part 2. Nanoscale materials based on graphene sheets;Reviews on Clinical Pharmacology and Drug Therapy;2023-03-28

5. Cytochrome P450 and flavin-containing monooxygenase enzymes are responsible for differential oxidation of the anti-thyroid-cancer drug vandetanib by human and rat hepatic microsomal systems;Environmental Toxicology and Pharmacology;2020-02

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