Precise tuning of disulphide crosslinking in mRNA polyplex micelles for optimising extracellular and intracellular nuclease tolerability

Author:

Dirisala Anjaneyulu1,Uchida Satoshi12,Tockary Theofilus A.1,Yoshinaga Naoto2,Li Junjie1,Osawa Shigehito1,Gorantla Lahari3,Fukushima Shigeto1,Osada Kensuke4,Kataoka Kazunori15

Affiliation:

1. Innovation Center of NanoMedicine (iCONM), Kawasaki Institute of Industrial Promotion, Kawasaki, Kanagawa, Japan;

2. Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, Bunkyo, Tokyo, Japan;

3. Department of Bioengineering, College of Engineering, University of Washington, Washington, USA;

4. National Institutes for Quantum and Radiology Science and Technology, Inage, Chiba, Japan;

5. Policy Alternatives Research Institute, The University of Tokyo, Bunkyo, Tokyo, Japan

Funder

Grants-in-Aid for Specially Promoted Research

Early-Career Scientists

Publisher

Informa UK Limited

Subject

Pharmaceutical Science

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