High sensitivity LC-MS profiling of antibody-drug conjugates with difluoroacetic acid ion pairing-Reference-Cited by-同舟云学术

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High sensitivity LC-MS profiling of antibody-drug conjugates with difluoroacetic acid ion pairing

Published:2019-09-10 Issue:8 Volume:11 Page:1358-1366
ISSN:1942-0862
Container-title:mAbs
language:en
Short-container-title:mAbs

Author:

Nguyen Jennifer M.¹²^ORCID,Smith Jacquelynn³,Rzewuski Susan²^ORCID,Legido-Quigley Cristina⁴,Lauber Matthew A.²^ORCID

Affiliation:

1. School of Science, University of Copenhagen, Frederiksberg, Denmark

2. Chemistry Technology Center, Waters Corporation, Milford, MA, USA

3. BioTherapeutics Pharmaceuticial Sciencies, Pfizer, Inc., Chesterfield, MO, USA

4. Systems Medicine, Steno Diabetes Center, Gentofte, Denmark

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

Link

https://www.tandfonline.com/doi/pdf/10.1080/19420862.2019.1658492

Reference32 articles.

1. Analytical tools for characterizing biopharmaceuticals and the implications for biosimilars

2. Schiel JE, Mire-Sluis A, Davis DL. Monoclonal Antibody Therapeutics: The Need for Biopharmaceutical Reference Materials. In: Shiel JE, Davis DL, Borisov OV, editors. State-of-the-Art and Emerging Technologies for Therapeutic Monoclonal Antibody Characterization Volume 1. Monoclonal Antibody Therapeutics: Structure, Function, and Regulatory Space. Washington (DC): The American Chemical Society; 2014. p. 1–34.

3. Development of a rapid RP-UHPLC–MS method for analysis of modifications in therapeutic monoclonal antibodies

4. Challenges and new frontiers in analytical characterization of antibody-drug conjugates

5. A new tool for monoclonal antibody analysis

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