In silico proof of principle of machine learning-based antibody design at unconstrained scale

Author:

Akbar Rahmad1ORCID,Robert Philippe A.1ORCID,Weber Cédric R.2ORCID,Widrich Michael3ORCID,Frank Robert1ORCID,Pavlović Milena4ORCID,Scheffer Lonneke4ORCID,Chernigovskaya Maria1ORCID,Snapkov Igor1ORCID,Slabodkin Andrei1ORCID,Mehta Brij Bhushan1ORCID,Miho Enkelejda5ORCID,Lund-Johansen Fridtjof1ORCID,Andersen Jan Terje16ORCID,Hochreiter Sepp37ORCID,Hobæk Haff Ingrid8,Klambauer Günter3ORCID,Sandve Geir Kjetil4ORCID,Greiff Victor1ORCID

Affiliation:

1. Department of Immunology, Oslo University Hospital Rikshospitalet and University of Oslo, Norway

2. Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland

3. Ellis Unit Linz and Lit Ai Lab, Institute for Machine Learning, Johannes Kepler University Linz, Linz, Austria

4. Department of Informatics, University of Oslo, Oslo, Norway

5. Institute of Medical Engineering and Medical Informatics, School of Life Sciences, FHNW University of Applied Sciences and Arts Northwestern Switzerland, Muttenz, Switzerland

6. Institute of Clinical Medicine, Department of Pharmacology, University of Oslo, Oslo, Norway

7. Institute of Advanced Research in Artificial Intelligence (IARAI), Austria

8. Department of Mathematics, University of Oslo, Oslo, Norway

Funder

the Leona M.and Harry B.Helmsley Charitable Trust

UiO World-Leading Research Community

LifeScience Convergence Environment Immunolingo

EU Horizon 2020 iReceptorplus

Research Council of Norway FRIPRO

Research Council of Norway IKTPLUSS

Norwegian Cancer Society

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

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