Cost-effectiveness of pembrolizumab for the first-line treatment of patients with unresectable or metastatic MSI-H/dMMR colorectal cancer in the United States

Author:

Aguiar-Ibáñez Raquel1ORCID,Hardern Chloë2,van Hees Frank3,Lee Dawn2ORCID,Patel Anubhav4,Chhabra Nitika4,Baluni Gargi4,Amonkar Mayur5ORCID,Lai Yizhen5,Xu Ruifeng5,Massaad Rachid6,Fogelman David5

Affiliation:

1. Merck Canada Inc., Kirkland, QC, Canada

2. BresMed Health Solutions Ltd., Sheffield, UK

3. BresMed Health Solutions Ltd, Utrecht, Netherlands

4. Complete HEOR Solutions (CHEORS), North Wales, PA, USA

5. Merck & Co., Inc., Kenilworth, NJ, USA

6. MSD (Europe) Inc., Brussels, Belgium

Publisher

Informa UK Limited

Subject

Health Policy

Reference38 articles.

1. National Cancer Institute. Cancer stat facts: colorectal cancer; 29 July 2021. Available from: https://seer.cancer.gov/statfacts/html/colorect.html.

2. Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade

3. Mismatch Repair Status and BRAF Mutation Status in Metastatic Colorectal Cancer Patients: A Pooled Analysis of the CAIRO, CAIRO2, COIN, and FOCUS Studies

4. National Comprehensive Cancer Network. Clinical practice guidelines in oncology (NCCN Guidelines) – rectal cancer; version 1.2021; 2021 [accessed 2021 July 6]. Available from: https://www.nccn.org/professionals/physician_gls/pdf/rectal.pdf.

5. National Comprehensive Cancer Network. Clinical practice guidelines in oncology (NCCN Guidelines) – colon cancer; version 2.2021; 2021 [accessed 2021 Jul 6]. Available from: https://www.nccn.org/professionals/physician_gls/pdf/colon.pdf.

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